Transport Models ================ .. module:: microscopic_gating.transport This module implements transport models that connect bridge dynamics to effective diffusion coefficients. Jump Diffusion -------------- .. autoclass:: JumpDiffusion :members: :member-order: bysource :show-inheritance: Poisson Escape Averaging ------------------------ .. autoclass:: PoissonEscapeAveraging :members: :member-order: bysource :show-inheritance: Concentration Dependent Diffusion --------------------------------- .. autoclass:: ConcentrationDependentDiffusion :members: :member-order: bysource :show-inheritance: Theory Background ----------------- Jump Diffusion Mapping ~~~~~~~~~~~~~~~~~~~~~~ The residence time and effective diffusion are related to the escape rate: .. math:: \tau_{\text{res}} = \frac{1}{k_{\text{esc}}} D_{\text{eff}}(n_b) = \frac{\ell^2}{2d} k_{\text{esc}}(n_b) where :math:`\ell` is the jump length and :math:`d` is the spatial dimension. Poisson Averaging ~~~~~~~~~~~~~~~~~ When the escape rate depends exponentially on bridge count: .. math:: k_{\text{esc}}(n_b) = \tilde{k}_0 e^{-\alpha n_b} The Poisson-averaged rate has a closed form: .. math:: k_{\text{esc}}(\phi) = \tilde{k}_0 \exp[-\lambda(1-e^{-\alpha})] Concentration-Dependent Diffusion ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ The full expression for effective diffusion: .. math:: D_{\text{eff}}(\phi) = D_{\text{free}} \exp[-\lambda(\phi)(1-e^{-\beta\epsilon_{\text{eff}}})]